<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Biesso, A.</style></author><author><style face="normal" font="default" size="100%">Qian, Wei</style></author><author><style face="normal" font="default" size="100%">Huang, Xiaohua</style></author><author><style face="normal" font="default" size="100%">El-Sayed, Mostafa A</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Gold Nanoparticles Surface Plasmon Field Effects on the Proton Pump Process of the Bacteriorhodopsin Photosynthesis</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of the American Chemical Society</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Feb</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">7</style></number><volume><style face="normal" font="default" size="100%">131</style></volume><pages><style face="normal" font="default" size="100%">2442-+</style></pages><isbn><style face="normal" font="default" size="100%">0002-7863</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">The rate of the proton pump of bacteriorhodopsin photosynthetic system is examined in the presence of a gold nanorod plasmon field. It is found that while the rate of the proton dissociation from the protonated Schiff base is not affected, the rate of its reprotonation increases. These results are qualitatively discussed in terms of several possible mechanisms.</style></abstract><accession-num><style face="normal" font="default" size="100%">WOS:000263576100012</style></accession-num><notes><style face="normal" font="default" size="100%">Biesso, Arianna Qian, Wei Huang, Xiaohua El-Sayed, Mostafa A.</style></notes><electronic-resource-num><style face="normal" font="default" size="100%">10.1021/ja8088873</style></electronic-resource-num></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Huang, Xiaohua</style></author><author><style face="normal" font="default" size="100%">Neretina, Svetlana</style></author><author><style face="normal" font="default" size="100%">El-Sayed, Mostafa A</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications</style></title><secondary-title><style face="normal" font="default" size="100%">Advanced Materials</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Dec</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">48</style></number><volume><style face="normal" font="default" size="100%">21</style></volume><pages><style face="normal" font="default" size="100%">4880-4910</style></pages><isbn><style face="normal" font="default" size="100%">0935-9648</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Noble metal nanoparticles; are capable of confining resonant photons in such a manner as to induce coherent surface plasmon oscillation of their conduction band electrons, a phenomenon leading to two important properties. Firstly, the confinement of the photon to the nanoparticle&#039;s dimensions leads to a large increase in its electromagnetic field and consequently great enhancement of all the nanoparticle&#039;s radiative properties, such as absorption and scattering. Moreover, by confining the photon&#039;s wavelength to the nanoparticle&#039;s small dimensions, there exists enhanced imaging resolving powers, which extend well below the diffraction limit, a property of considerable importance in potential device applications. Secondly, the strongly absorbed light by the nanoparticles is followed by a rapid dephasing of the coherent electron motion in tandem with an equally rapid energy transfer to the lattice, a process integral to the technologically relevant photothermal properties of plasmonic nanoparticles. Of all the possible nanoparticle shapes, gold nanorods are especially intriguing as they offer strong plasmonic fields while exhibiting excellent tunability and biocompatibility. We begin this review of gold nanorods by summarizing their radiative and nonradiative properties. Their various synthetic methods are then outlined with an emphasis on the seed-mediated chemical growth. In particular, we describe nanorod spontaneous self-assembly, chemically driven assembly, and polymer-based alignment. The final section details current studies aimed at applications in the biological and biomedical fields.</style></abstract><accession-num><style face="normal" font="default" size="100%">WOS:000273359300001</style></accession-num><notes><style face="normal" font="default" size="100%">Huang, Xiaohuo Neretina, Svetiana El-Sayed, Mostafa A.</style></notes><electronic-resource-num><style face="normal" font="default" size="100%">10.1002/adma.200802789</style></electronic-resource-num></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dickerson, E. B.</style></author><author><style face="normal" font="default" size="100%">Dreaden, Erik</style></author><author><style face="normal" font="default" size="100%">Huang, Xiaohua</style></author><author><style face="normal" font="default" size="100%">El Sayed, I.H.</style></author><author><style face="normal" font="default" size="100%">Chu, H. H.</style></author><author><style face="normal" font="default" size="100%">Pushpanketh, S.</style></author><author><style face="normal" font="default" size="100%">McDonald, J. F.</style></author><author><style face="normal" font="default" size="100%">El-Sayed, Mostafa A</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice</style></title><secondary-title><style face="normal" font="default" size="100%">Cancer Letters</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2008</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Sep</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">1</style></number><volume><style face="normal" font="default" size="100%">269</style></volume><pages><style face="normal" font="default" size="100%">57-66</style></pages><isbn><style face="normal" font="default" size="100%">0304-3835</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Plasmonic photothermal therapy (PPTT) is a minimally-invasive oncological treatment strategy in which photon energy is selectively administered and converted into heat sufficient to induce cellular hyperthermia. The present work demonstrates the feasibility of in vivo PPTT treatment of deep-tissue malignancies using easily-prepared plasmonic gold nanorods and a small, portable, inexpensive near-infrared (NIR) laser. Dramatic size decreases in squamous cell carcinoma xenografts were observed for direct (P &lt; 0.0001) and intravenous (P &lt; 0.0008) administration of pegylated gold nanorods in nu/nu mice. Inhibition of average tumor growth for both delivery methods was observed over a 13-day period, with resorption of &gt;57% of the directly-injected tumors and 25% of the intravenously-treated tumors. Published by Elsevier Ltd.</style></abstract><accession-num><style face="normal" font="default" size="100%">WOS:000259847100007</style></accession-num><notes><style face="normal" font="default" size="100%">Dickerson, Erin B. Dreaden, Erik C. Huang, Xiaohua El-Sayed, Ivan H. Chu, Hunghao Pushpanketh, Sujatha McDonald, John F. El-Sayed, Mostafa A.</style></notes><electronic-resource-num><style face="normal" font="default" size="100%">10.1016/j.canlet.2008.04.026</style></electronic-resource-num></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Huang, Xiaohua</style></author><author><style face="normal" font="default" size="100%">Jain, Prashant K</style></author><author><style face="normal" font="default" size="100%">El Sayed, I.H.</style></author><author><style face="normal" font="default" size="100%">El-Sayed, Mostafa A</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Gold nanoparticles: interesting optical properties and recent applications in cancer diagnostic and therapy</style></title><secondary-title><style face="normal" font="default" size="100%">Nanomedicine</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2007</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Oct</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">5</style></number><volume><style face="normal" font="default" size="100%">2</style></volume><pages><style face="normal" font="default" size="100%">681-693</style></pages><isbn><style face="normal" font="default" size="100%">1743-5889</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Recent years have seen tremendous progress in the design and study of nanomaterials geared towards biological and biomedical applications, most notable among these being the noble metal nanoparticles. In this review, we outline the surface-plasmon resonance-enhanced optical properties of colloidal gold nanoparticles directed towards recent biomedical applications with an emphasis on cancer diagnostics and therapeutics. Methods of molecular-specific diagnostics/detection of cancer, including strongly enhanced surface plasmon resonance light-scattering, surface-enhanced emission of gold nanorods and surf ace-enhanced Raman scattering, are described. We also discuss the plasmonic photothermal therapy of cancer achieved by using the strongly enhanced surface-plasmon resonance absorption of gold nanospheres and nanorods.</style></abstract><accession-num><style face="normal" font="default" size="100%">WOS:000251038200016</style></accession-num><notes><style face="normal" font="default" size="100%">Huang, Xiaohua Jain, Prashant K. El-Sayed, Ivan H. El-Sayed, Mostafa A.</style></notes><electronic-resource-num><style face="normal" font="default" size="100%">10.2217/17435889.2.5.681</style></electronic-resource-num></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Huang, Xiaohua</style></author><author><style face="normal" font="default" size="100%">El Sayed, I.H.</style></author><author><style face="normal" font="default" size="100%">Yi, X. B.</style></author><author><style face="normal" font="default" size="100%">El-Sayed, Mostafa A</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Gold nanoparticles: Catalyst for the oxidation of NADH to NAD(+)</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Photochemistry and Photobiology B-Biology</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2005</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Nov</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">2</style></number><volume><style face="normal" font="default" size="100%">81</style></volume><pages><style face="normal" font="default" size="100%">76-83</style></pages><isbn><style face="normal" font="default" size="100%">1011-1344</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Nicotinamide adenine dinucleotide is an important coenzyme involved in the production of ATP, the fuel of energy, in every cell. It alternates between the oxidized form NAD(+) and the reduced form dihydronicotinamide adenine dinucleotide (NADH) and serves as a hydrogen and electron carrier in the cellular respiratory processes. In the present work, the catalytic effect of gold nanoparticles on the oxidization of NADH to NAD(+) was investigated. The addition of gold nanoparticles was found to quench the NADH fluorescence intensities but had no effect on the fluorescence lifetime. This suggested that the fluorescence quenching was not due to coupling with the excited state, but due to changing the ground state of NADH. The intensity of the 340 nm absorption band of NADH was found to decrease while that of the 260 nm band of NAD+ was found to increase as the concentration of gold nanoparticles increased. This conversion reaction was further supported by nuclear magnetic resonance and mass spectroscopy. The effect of the addition of NADH was found to slightly red shift and increase the intensity of the surface plasmon absorption band of gold nanoparticles at 520 nm. This gives a strong support that the conversion of NADH to NAD(+) is occurring on the surface of the gold nanoparticles, i.e. NADH is surface catalyzed by the gold nanoparticles. The catalytic property of this important reaction might have important future applications in biological and medical fields. (c) 2005 Elsevier B.V. All rights reserved.</style></abstract><accession-num><style face="normal" font="default" size="100%">WOS:000233023900002</style></accession-num><notes><style face="normal" font="default" size="100%">Huang, XH El-Sayed, IH Yi, XB El-Sayed, MA</style></notes><electronic-resource-num><style face="normal" font="default" size="100%">10.1016/j.jphotobiol.2005.05.010</style></electronic-resource-num></record></records></xml>