TY - JOUR T1 - Gold Nanorod-Photothermal Therapy Alters Cell Junctions and Actin Network in Inhibiting Cancer Cell Collective Migration JF - ACS nano Y1 - 2018 A1 - Y. Wu A1 - Ali, M. R. K. A1 - B. Dong A1 - T. Han A1 - K. Chen A1 - J. Chen A1 - Y. Tang A1 - N. Fang A1 - F. Wang A1 - El-Sayed, M. A. ER - TY - JOUR T1 - Treatment of natural mammary gland tumors in canines and felines using gold nanorods-assisted plasmonic photothermal therapy to induce tumor apoptosis JF - International journal of nanomedicine Y1 - 2016 A1 - Ali, M. R. K. A1 - et al. ER - TY - JOUR T1 - The Most Effective Gold Nanorod Size for Plasmonic Photothermal Therapy: Theory and In Vitro Experiments JF - Journal of Physical Chemistry B Y1 - 2014 A1 - Mackey, M. A. A1 - Ali, M. R. K. A1 - Austin, Lauren A1 - Near, R. D. A1 - El-Sayed, M. A. VL - 118 SN - 1520-6106 N1 - Mackey, Megan A. Ali, Moustafa R. K. Austin, Lauren A. Near, Rachel D. El-Sayed, Mostafa A. J1 - J. Phys. Chem. B M3 - 10.1021/jp409298f ER - TY - JOUR T1 - Synthesis and Optical Properties of Small Au Nanorods Using a Seedless Growth Technique JF - Langmuir Y1 - 2012 A1 - Ali, M. R. K. A1 - Snyder, B. A1 - El-Sayed, M. A. AB - Gold nanoparticles have shown potential in photothermal cancer therapy and optoelectronic technology. In both applications, a call for small size nanorods is warranted. In the present work, a one-pot seedless synthetic technique has been developed to prepare relatively small monodisperse gold nanorods with average dimensions (length x width) of 18 x 4.5 nm, 25 x 5 nm, 15 x 4.5 nm, and 10 x 2.5 nm. In this method, the pH was found to play a crucial role in the monodispersity of the nanorods when the NaBH4 concentration of the growth solution was adjusted to control the reduction rate of the gold ions. At the optimized pH and NaBH4 concentrations, smaller gold nanorods were produced by adjusting the CTAB concentration in the growth solution. In addition, the concentration of silver ions in the growth solution was found to be pivotal in controlling the aspect ratio of the nanorods. The extinction coefficient values for the small gold nanorods synthesized with three different aspect ratios were estimated using the absorption spectra, size distributions, and the atomic spectroscopic analysis data. The previously accepted relationships between the extinction coefficient or the longitudinal band wavelength values and the nanorods' aspect ratios found for the large nanorods do not extend to the small size domain reported in the present work. The failure of extending these relationships over larger sizes is a result of the interaction of light with the large rods giving an extinction band which results mostly from scattering processes while the extinction of the small nanorods results from absorption processes. VL - 28 SN - 0743-7463 M3 - 10.1021/la301387p ER - TY - JOUR T1 - Synthesis and Optical Properties of Small Au Nanorods Using a Seedless Growth Technique JF - Langmuir Y1 - 2012 A1 - Ali, M. R. K. A1 - Snyder, B. A1 - El-Sayed, M. A. AB - Gold nanoparticles have shown potential in photothermal cancer therapy and optoelectronic technology. In both applications, a call for small size nanorods is warranted. In the present work, a one-pot seedless synthetic technique has been developed to prepare relatively small monodisperse gold nanorods with average dimensions (length x width) of 18 x 4.5 nm, 25 x 5 nm, 15 x 4.5 nm, and 10 x 2.5 nm. In this method, the pH was found to play a crucial role in the monodispersity of the nanorods when the NaBH4 concentration of the growth solution was adjusted to control the reduction rate of the gold ions. At the optimized pH and NaBH4 concentrations, smaller gold nanorods were produced by adjusting the CTAB concentration in the growth solution. In addition, the concentration of silver ions in the growth solution was found to be pivotal in controlling the aspect ratio of the nanorods. The extinction coefficient values for the small gold nanorods synthesized with three different aspect ratios were estimated using the absorption spectra, size distributions, and the atomic spectroscopic analysis data. The previously accepted relationships between the extinction coefficient or the longitudinal band wavelength values and the nanorods' aspect ratios found for the large nanorods do not extend to the small size domain reported in the present work. The failure of extending these relationships over larger sizes is a result of the interaction of light with the large rods giving an extinction band which results mostly from scattering processes while the extinction of the small nanorods results from absorption processes. VL - 28 SN - 0743-7463 N1 - Times Cited: 2Ali, Moustafa R. K. Snyder, Brian El-Sayed, Mostafa A. M3 - 10.1021/la301387p ER -