TY - JOUR T1 - Gold nanomaterials as key suppliers in biological and chemical sensing, catalysis, and medicine JF - Biochimica et Biophysica Acta (BBA)-General Subjects Y1 - 2020 A1 - Falahati, M. A1 - Attar, F. A1 - Sharifi, M. A1 - Saboury, A.A. A1 - Salihi, A. A1 - Aziz, F.M. A1 - Kostova, I. A1 - Burda, C. A1 - Priecel, P. A1 - Lopez-Sanchez, J.A. A1 - Laurent, S. A1 - Hooshmand, N. A1 - El-Sayed, M.A. ER - TY - JOUR T1 - Plasmonic and chiroplasmonic nanobiosensors based on gold nanoparticles JF - Talanta Y1 - 2020 A1 - Sharifi, M. A1 - Hosseinali, S.H. A1 - Alizadeh, R.H. A1 - Hasan, A. A1 - Attar, F. A1 - Salihi, A. A1 - Shekha, M.S. A1 - Amen, K.M. A1 - Aziz, F.M. A1 - Saboury, A.A. A1 - Akhtari, K. A1 - Taghizadeh, A. A1 - Hooshmand, N. A1 - El-Sayed, M. A. A1 - Falahati, M. ER - TY - JOUR T1 - Gold nanoparticles in biological optical imaging JF - Nano Today Y1 - 2019 A1 - Wu, Y. A1 - Ali, M.R. A1 - Chen, K. A1 - Fang, N. A1 - El-Sayed, M.A. ER - TY - JOUR T1 - Gold Nanorod-Assisted Photothermal Therapy Decreases Bleeding during Breast Cancer Surgery in Dogs and Cats JF - Cancers Y1 - 2019 A1 - Ali, M.R. A1 - Farghali, H.A. A1 - Wu, Y. A1 - El-Sayed, I. A1 - Osman, A.H. A1 - Selim, S.A. A1 - El-Sayed, M.A. ER - TY - JOUR T1 - Plasmonic gold nanoparticles: Optical manipulation, imaging, drug delivery and therapy JF - Journal of Controlled Release Y1 - 2019 A1 - Sharifi, M. A1 - Attar, F. A1 - Saboury, A.A. A1 - Akhtari, K. A1 - Hooshmand, N. A1 - Hasan, A. A1 - El-Sayed, M.A. A1 - Falahati, M. ER - TY - JOUR T1 - Defect engineering in 1D Ti–W oxide nanotube arrays and their correlated photoelectrochemical performance JF - Physical Chemistry Chemical Physics Y1 - 2018 A1 - A.A. Abdelhafiz A1 - M.A. Ganzoury A1 - Amer, A. W. A1 - A.A. Faiad A1 - A.M. Khalifa A1 - S.Y. AlQaradawi A1 - El-Sayed, M. A. A1 - Alamgir, F. M. A1 - Allam, N. K. ER - TY - JOUR T1 - Gold Nanorod-Photothermal Therapy Alters Cell Junctions and Actin Network in Inhibiting Cancer Cell Collective Migration JF - ACS nano Y1 - 2018 A1 - Y. Wu A1 - Ali, M. R. K. A1 - B. Dong A1 - T. Han A1 - K. Chen A1 - J. Chen A1 - Y. Tang A1 - N. Fang A1 - F. Wang A1 - El-Sayed, M. A. ER - TY - JOUR T1 - P‐Glycoprotein‐Dependent Trafficking of Nanoparticle‐Drug Conjugates JF - Small Y1 - 2014 A1 - Dreaden, Erik C. A1 - Raji, Idris O A1 - Austin, Lauren A1 - Fathi, Shaghayegh A1 - Mwakwari, Sandra C A1 - Humphries, William H A1 - Kang, Bin A1 - Oyelere, Adegboyega K A1 - El‐Sayed, Mostafa A VL - 10 SN - 1613-6829 ER - TY - JOUR T1 - Electron transfer process in fluorescein-dispersing titania gel films observed by time-resolved fluorescence spectroscopy JF - The Journal of Physical Chemistry C Y1 - 2013 A1 - Setiawan, Rudi Agus A1 - Nishikiori, Hiromasa A1 - Uesugi, Yohei A1 - Miyashita, Kyohei A1 - El-Sayed, Mostafa A. A1 - Fujii, Tsuneo VL - 117 SN - 1932-7447 ER - TY - JOUR T1 - Tissue Distribution and Efficacy of Gold Nanorods Coupled with Laser Induced Photoplasmonic Therapy in Ehrlich Carcinoma Solid Tumor Model JF - Plos One Y1 - 2013 A1 - El-Sayed, M. A. A1 - Shabaka, A. A. A1 - El-Shabrawy, O. A. A1 - Yassin, N. A. A1 - Mahmoud, S. S. A1 - El-Shenawy, S. M. A1 - Al-Ashqar, E. A1 - Eisa, W. H. A1 - Farag, N. M. A1 - El-Shaer, M. A. A1 - Salah, N. A1 - Al-Abd, A. M. AB - Gold nanorods (GNR) within tumor microregions are characterized by their ability to absorb near IR light and emit heat in what is called photoplasmonic effect. Yet, the efficacy of nanoparticles is limited due to intratumoral tissue distribution reasons. In addition, distribution of GNRs to normal tissue might result in non specific toxicity. In the current study, we are assessing the intratumoral and tissue distribution of PEGylated GNRs on the top of its antitumor characteristics when given intravenously or intratumoral to solid tumor bearing mice and coupled with laser photoplasmonic sessions. PEGylated GNRs with a longitudinal size of less than 100 nm were prepared with aspect ratio of 4.6 showing strong surface plasmon absorption at wavelength 800 nm. Pharmacokinetics of GNR after single I.V. administration (0.1 mg/kg) showed very short systemic circulating time (less than 3 h). On the other hand, tissue distribution of I.V. GNR (0.1 mg/kg) to normal animals showed preferential deposition in spleen tissue. Repeated administration of I.V. GNR resulted in preferential accumulation in both liver and spleen tissues. In addition, I.V. administration of GNR to Ehrlich carcinoma tumor bearing mice resulted in similar tissue distribution; tumor accumulation and anti-tumor effect compared to intratumoral administration. In conclusion, the concentration of GNR achieved within tumors microregions after I.V. administration was comparable to I.T. administration and sufficient to elicit tumoral growth arrest when coupled with laser-aided photoplasmonic treatment. VL - 8 SN - 1932-6203 N1 - El-Sayed, Mostafa A. Shabaka, Ali A. El-Shabrawy, Osama A. Yassin, Nemat A. Mahmoud, Sawsan S. El-Shenawy, Siham M. Al-Ashqar, Emad Eisa, Wael H. Farag, Niveen M. El-Shaer, Marwa A. Salah, Nabila Al-Abd, Ahmed M. M3 - 10.1371/journal.pone.0076207 ER - TY - JOUR T1 - Application of surface enhanced Raman spectroscopy to the study of SOFC electrode surfaces JF - Physical Chemistry Chemical Physics Y1 - 2012 A1 - Li, X. X. A1 - Blinn, K. A1 - Fang, Y. C. A1 - Liu, M. F. A1 - Mahmoud, M A A1 - Cheng, S. A1 - Bottomley, L. A. A1 - El-Sayed, M. A1 - Liu, M. L. AB - SERS provided by sputtered silver was employed to detect trace amounts of chemical species on SOFC electrodes. Considerable enhancement of Raman signal and lowered detection threshold were shown for coked nickel surfaces, CeO2 coatings, and cathode materials (LSM and LSCF), suggesting a viable approach to probing electrode degradation and surface catalytic mechanism. VL - 14 SN - 1463-9076 N1 - Times Cited: 3Li, Xiaxi Blinn, Kevin Fang, Yingcui Liu, Mingfei Mahmoud, Mahmoud A. Cheng, Shuang Bottomley, Lawrence A. El-Sayed, Mostafa Liu, Meilin M3 - 10.1039/c2cp40091j ER - TY - JOUR T1 - Photoelectric Conversion Properties of Dye-Sensitized Solar Cells Using Dye-Dispersing Titania JF - Journal of Physical Chemistry C Y1 - 2012 A1 - Nishikiori, H. A1 - Uesugi, Y. A1 - Setiawan, R. A. A1 - Fujii, T. A1 - Qian, W. A1 - El-Sayed, M. A. AB - The time-resolved fluorescence and photoelectrochemical properties of dye-sensitized solar cells using crystalline titania electrodes coated with N3 dye-dispersing amorphous titania gel were investigated to clarify the influence of the dye titania interaction and electron transfer on their photoelectric conversion performance. The photocurrent quantum efficiency of the electrodes was remarkably increased by a steam treatment due to the crystallization and densification of the amorphous titania layer compared to that of the untreated electrode. The electron injection from the dye to the crystalline titania foundation via the steam-treated titania dispersing the dye was confirmed to be more efficient than that in the conventional electrodes. The dye-dispersing titania layer prevented interaction between the dye molecules and back electron transfer from the titania to the electrolyte. The charge separation and photoelectric conversion performance of the dye-sensitized solar cells were improved by forming the specific dye-dispersing titania layer. VL - 116 SN - 1932-7447 N1 - Times Cited: 1Nishikiori, Hiromasa Uesugi, Yohei Setiawan, Rudi Agus Fujii, Tsuneo Qian, Wei El-Sayed, Mostafa A. M3 - 10.1021/jp2094388 ER - TY - JOUR T1 - Influence of Steam Treatment on Dye-Titania Complex Formation and Photoelectric Conversion Property of Dye-Doped Titania Gel JF - Journal of Physical Chemistry C Y1 - 2011 A1 - Nishikiori, H. A1 - Uesugi, Y. A1 - Takami, S. A1 - Setiawan, R. A1 - Fujii, T. A1 - Qian, Wei A1 - El-Sayed, Mostafa A AB - Xanthene dye molecules form a chelate complex with the titanium species on the titania surface in dye-titania systems. The complex formation causes a fast electron injection into the titania conduction band. In this study, simple spectroscopic and photocurrent measurements of the xanthene dye-doped titania gels prepared by the sol-gel method were conducted in order to clarify the influence of a steam treatment on the dye-titania interaction and electron transfer. The photocurrent quantum efficiency of the fluorescein-doped electrode was remarkably increased by the steam treatment compared to that of the untreated electrode consisting of an amorphous titania gel. The photocurrent action spectrum was red-shifted, and the short circuit photocurrent and open circuit voltage values increased with the steam treatment time. The steam treatment promoted the dye-titania complex formation, a negative shift in the conduction band potential of the titania, and the electron injection from the dye to the titania. VL - 115 SN - 1932-7447 N1 - Nishikiori, Hiromasa Uesugi, Yohei Takami, Shohei Setiawan, RudiAgus Fujii, Tsuneo Qian, Wei El-Sayed, Mostafa A. M3 - 10.1021/jp109958z ER - TY - JOUR T1 - Change in titania structure from amorphousness to crystalline increasing photoinduced electron-transfer rate in dye-titania system JF - Journal of Physical Chemistry C Y1 - 2007 A1 - Nishikiori, H. A1 - Qian, Wei A1 - El-Sayed, Mostafa A A1 - Tanaka, N. A1 - Fujii, T. AB - Thin titania gel films containing well-dispersed fluorescein dye were prepared by the sol-gel method and treated with steam to promote crystal growth of the titania particles. It is known that steam treatment converts the titania structure from amorphousness to crystalline. In the present study, such change is found to increase the rate of the photoinduced electron transfer from and to dispersed fluorescein dye molecules. VL - 111 SN - 1932-7447 N1 - Nishikiori, Hiromasa Qian, Wei El-Sayed, Mostafa A. Tanaka, Nobuaki Fujii, Tsuneo M3 - 10.1021/jp072625q ER - TY - JOUR T1 - Hot electron relaxation dynamics of gold nanoparticles embedded in MgSO4 powder compared to solution: The effect of the surrounding medium JF - Journal of Physical Chemistry B Y1 - 2002 A1 - Link, Stephan A1 - Furube, A. A1 - Mohamed, MB A1 - Asahi, T. A1 - Masuhara, H. A1 - El-Sayed, Mostafa A AB - To test the influence of the surrounding medium on the relaxation dynamics of the plasmon band bleach recovery of gold nanoparticles after excitation with femtosecond laser pulses, we embedded 14.5 and 12.1 nm colloidal gold nanoparticles (synthesized electrochemically) in MgSO4 powder and investigated these samples by femtosecond diffuse reflectance spectroscopy. By measuring the relaxation dynamics over a wide range of excitation energies, we found that the fast decay component is slower by about a factor of 2 for the particles in the MgSO4 powder compared to those in solution while no significant change in the slow decay component is observed. In agreement with this observation, we found that adding solvent to the particles embedded in the powder caused a decrease in the relaxation time from about 10 ps to 5 ps for the fast decay component. This leads to the conclusion that the electron-phonon relaxation in these gold nanoparticles depends on the chemical nature and/or physical phase (solid vs solution) of the surrounding medium. A discussion of this in terms of the type of phonon involved, and the nature of the electron-phonon and phonon-phonon relaxation processes is discussed. To our knowledge, this also presents the first time that a transient bleach could be observed by diffuse reflectance spectroscopy. VL - 106 SN - 1520-6106 N1 - Link, S Furube, A Mohamed, MB Asahi, T Masuhara, H El-Sayed, MA M3 - 10.1021/jp013311k ER - TY - JOUR T1 - Visible to infrared luminescence from a 28-atom gold cluster JF - Journal of Physical Chemistry B Y1 - 2002 A1 - Link, Stephan A1 - Beeby, A. A1 - FitzGerald, S. A1 - El-Sayed, Mostafa A A1 - Schaaff, T. G. A1 - Whetten, R. L. AB - The luminescence properties of chemically prepared gold nanoclusters, each composed of a 28-atom core and a glutathione (GSH) adsorbate layer consisting of 16 molecules, were investigated. These clusters show a distinct absorption onset at 1.3 eV corresponding to the opening of an electronic gap within the conduction band (HOMO-LUMO gap). Here we report on the radiative properties of these molecular-like Bald clusters. By using a combination of different detectors with sensitivities in the visible to the infrared (2.0-0.8 eV), a broad luminescence extending over this entire spectral range was observed. Our results further suggest that the luminescence can be separated into two bands with maxima around 1.5 and 1.15 eV indicating that radiative recombination between the ground state and two distinctively different excited states takes place. The: origin of the observed luminescence bands is discussed using a solid state as well as a molecular model for the electronic structure and relaxation of the clusters. The total quantum yield of the luminescence: as measured at ambient temperature was approximated to be about (3.5 +/- 1.0) x 10(-3). VL - 106 SN - 1520-6106 N1 - Link, S Beeby, A FitzGerald, S El-Sayed, MA Schaaff, TG Whetten, RL M3 - 10.1021/jp014259v ER - TY - JOUR T1 - Laser Multiphoton Dissociation Ionization of Acrolein Clusters JF - The Journal of Physical Chemistry A Y1 - 1997 A1 - Morita, Hiroshi A1 - Freitas, John E. A1 - El-Sayed, Mostafa A AB - Clusters of acrolein, C3H4O, are formed by supersonic expansion techniques. The acrolein clusters are ionized and decomposed by 193 nm light from an excimer laser and detected by time-of-flight mass spectrometry. The dominant channel of decomposition involves the loss of a carbon atom from all the clusters. The loss of C2, C3, and even up to C6 is also observed from larger clusters. The presence of clusters with more hydrogen atoms than expected for multiples of acrolein molecules suggests that reactions within the cluster and evaporation are important processes. The mechanisms of the dissociation routes are discussed in terms of ladder and ladder-switching processes within individual molecules within the cluster.Clusters of acrolein, C3H4O, are formed by supersonic expansion techniques. The acrolein clusters are ionized and decomposed by 193 nm light from an excimer laser and detected by time-of-flight mass spectrometry. The dominant channel of decomposition involves the loss of a carbon atom from all the clusters. The loss of C2, C3, and even up to C6 is also observed from larger clusters. The presence of clusters with more hydrogen atoms than expected for multiples of acrolein molecules suggests that reactions within the cluster and evaporation are important processes. The mechanisms of the dissociation routes are discussed in terms of ladder and ladder-switching processes within individual molecules within the cluster. PB - American Chemical Society VL - 101 SN - 1089-5639 UR - http://dx.doi.org/10.1021/jp9605010 CP - 20 N1 - doi: 10.1021/jp9605010 J1 - J. Phys. Chem. A M3 - doi: 10.1021/jp9605010 ER - TY - JOUR T1 - Enhancement of Metallic Silver Monomer Evaporation by the Adhesion of Polar Molecules to Silver Nanocluster Ions JF - The Journal of Physical Chemistry Y1 - 1995 A1 - Fagerquist, Clifton K. A1 - Sensharma, Dilip K. A1 - El-Sayed, Mostafa A A1 - Rubio, Angel A1 - Cohen, Marvin L. AB - View http://dx.doi.org/10.1021/j100019a061 for article's front page in lieu of an abstract PB - American Chemical Society VL - 99 SN - 0022-3654 UR - http://dx.doi.org/10.1021/j100019a061 CP - 19 N1 - doi: 10.1021/j100019a061 J1 - J. Phys. Chem. M3 - doi: 10.1021/j100019a061 ER - TY - JOUR T1 - The Wavelength Dependence of the Rates of Internal Energy Redistribution during the Photodissociation of 3-Iodopyridine JF - The Journal of Physical Chemistry Y1 - 1995 A1 - Freitas, John E. A1 - El-Sayed, Mostafa A A1 - Hwang, Hyun Jin AB - View http://dx.doi.org/10.1021/j100019a024 for article's front page in lieu of an abstract PB - American Chemical Society VL - 99 SN - 0022-3654 UR - http://dx.doi.org/10.1021/j100019a024 CP - 19 N1 - doi: 10.1021/j100019a024 J1 - J. Phys. Chem. M3 - doi: 10.1021/j100019a024 ER -