Suzuki cross-coupling reactions catalyzed by palladium nanoparticles in aqueous solution

TitleSuzuki cross-coupling reactions catalyzed by palladium nanoparticles in aqueous solution
Publication TypeJournal Article
Year of Publication2000
AuthorsLi, Y, Hong, XM, Collard, DM, EL-Sayed, MA
JournalOrganic Letters
Volume2
Pagination2385-2388
Date PublishedJul
ISBN Number1523-7060
Accession NumberWOS:000088346400053
Abstract

[GRAPHICS] Palladium nanoparticles stabilized by poly(N-vinyl-2-pyrrolidone) (PVP) are efficient catalysts for the Suzuki reactions in aqueous medium. The time dependence of the fluorescence intensity of the biphenyl product in the reaction between iodobenzene and phenylboronic acid is used to determine the initial rate of the catalytic reaction. The initial rate depends linearly on the concentration of Pd catalyst, suggesting that the catalytic reaction occurs on the surface of the Pd nanoparticles.

DOI10.1021/ol0061687